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Robust generalized sidelobe canceller based on eigenanalysis and a MaxSINR beamformer Research Articles

Quan-dong WANG, Liang-hao GUO, Wei-yu ZHANG, Sui-ling REN, Chao YAN

Frontiers of Information Technology & Electronic Engineering 2019, Volume 20, Issue 7,   Pages 975-987 doi: 10.1631/FITEE.1700367

Abstract: To avoid that collection procedure, we redesign the blocking matrix structure using an eigenanalysismethod to reconstruct the IPN covariance matrix from the samples.Additionally, a modified eigenanalysis reconstruction method based on the rank-one matrix assumptionThe blocking matrix is obtained by incorporating the effective reconstruction into the maximum signal-to-interferenceplus-noise

Keywords： Eigenanalysis     Interference-plus-noise covariance matrix reconstruction     Maximum signal-to-interference-plus-noiseratio criterion     Blocking matrix     Generalized sidelobe canceller     Direction of arrival mismatch    

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BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation

Frontiers of Medicine doi: 10.1007/s11684-023-0996-8

Abstract: OX40 is a costimulatory receptor that is expressed primarily on activated CD4+, CD8+, and regulatory T cells. The ligation of OX40 to its sole ligand OX40L potentiates T cell expansion, differentiation, and activation and also promotes dendritic cells to mature to enhance their cytokine production. Therefore, the use of agonistic anti-OX40 antibodies for cancer immunotherapy has gained great interest. However, most of the agonistic anti-OX40 antibodies in the clinic are OX40L-competitive and show limited efficacy. Here, we discovered that BGB-A445, a non-ligand-competitive agonistic anti-OX40 antibody currently under clinical investigation, induced optimal T cell activation without impairing dendritic cell function. In addition, BGB-A445 dose-dependently and significantly depleted regulatory T cells in vitro and in vivo via antibody-dependent cellular cytotoxicity. In the MC38 syngeneic model established in humanized OX40 knock-in mice, BGB-A445 demonstrated robust and dose-dependent antitumor efficacy, whereas the ligand-competitive anti-OX40 antibody showed antitumor efficacy characterized by a hook effect. Furthermore, BGB-A445 demonstrated a strong combination antitumor effect with an anti-PD-1 antibody. Taken together, our findings show that BGB-A445, which does not block OX40–OX40L interaction in contrast to clinical-stage anti-OX40 antibodies, shows superior immune-stimulating effects and antitumor efficacy and thus warrants further clinical investigation.

Keywords： BGB-A445     OX40     agonistic antibody     OX40L noncompetitive    

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Decellularized extracellular matrix mediates tissue construction and regeneration

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 56-82 doi: 10.1007/s11684-021-0900-3

Abstract: Contributing to organ formation and tissue regeneration, extracellular matrix (ECM) constituents provideContaining the crucial traits of the cellular microenvironment, ECM substitutes mediate cell–matrix interactions

Keywords： decellularized extracellular matrix     3D culture     organoids     tissue repair    

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Perspective of mixed matrix membranes for carbon capture

Shinji Kanehashi, Colin A. Scholes

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 3,   Pages 460-469 doi: 10.1007/s11705-019-1881-5

Abstract: Mixed matrix membranes (MMMs) have a composite structure that consists of polymers and fillers, therefore

Keywords： membranes     polymeric     mixed matrix     impurities    

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Strengthening of reinforced concrete beams using fiber-reinforced cementitious matrix systems fabricated

Frontiers of Structural and Civil Engineering   Pages 1100-1116 doi: 10.1007/s11709-023-0967-9

Abstract: The performance of a new fiber-reinforced cementitious matrix (FRCM) system developed using custom-designed

Keywords： fiber-reinforced cementitious matrix     flexural strengthening     shear strengthening     carbon fiber-reinforced    

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A dynamic model of mobile concrete pump boom based on discrete time transfer matrix method

Wu REN, Yunxin WU, Zhaowei ZHANG

Frontiers of Mechanical Engineering 2013, Volume 8, Issue 4,   Pages 360-366 doi: 10.1007/s11465-013-0280-8

Abstract: A dynamics model of a mobile concrete pump boom is established based on discrete time transfer matrixThe overall dynamic equation and transfer matrix of the model can be assembled by sub-structures A and

Keywords： multi-body     mobile concrete pump boom     discrete time transfer matrix method (DTTMM)     kinematic     dynamic     tip    

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Glycosylation of dentin matrix protein 1 is critical for fracture healing via promoting chondrogenesis

Hui Xue, Dike Tao, Yuteng Weng, Qiqi Fan, Shuang Zhou, Ruilin Zhang, Han Zhang, Rui Yue, Xiaogang Wang, Zuolin Wang, Yao Sun

Frontiers of Medicine 2019, Volume 13, Issue 5,   Pages 575-589 doi: 10.1007/s11684-019-0693-9

Abstract: Cartilage consists of both chondrocytes and extracellular matrix (ECM).The PG form of dentin matrix protein 1 (DMP1-PG) is involved in maintaining the health of articular cartilage

Keywords： fracture     extracellular matrix     dentin matrix protein 1     proteoglycan     cartilage    

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Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

Namita Gupta,N.D. Gupta,Akash Gupta,Saif Khan,Neha Bansal

Frontiers of Medicine 2015, Volume 9, Issue 1,   Pages 72-76 doi: 10.1007/s11684-014-0347-x

Abstract: Any imbalance between the matrix metalloproteinases (MMPs) secreted by neutrophils and tissue inhibitors

Keywords： matrix metalloproteinase-8     chronic periodontitis     pocket probing depth     clinical attachment level     gingival    

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Studies of fiber-matrix debonding

Navneet DRONAMRAJU,Johannes SOLASS,Jörg HILDEBRAND

Frontiers of Structural and Civil Engineering 2015, Volume 9, Issue 4,   Pages 448-456 doi: 10.1007/s11709-015-0316-8

Abstract: In this paper, the debonding of a single fiber-matrix system of carbon fiber reinforced composite (CFRPslip distance and artificial damping coefficient on the debonding length at the interface of the fiber-matrixLoad is applied on the matrix, tangential to the interface.

Keywords： single fibre     cohesive zone model     interface debonding     carbon fiber reinforced composite (CFRP)    

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A novel cataplasma matrix of traditional Chinese medicine

Jing TIAN, Xiaolei ZHANG, Xueqin ZHOU,

Frontiers of Chemical Science and Engineering 2010, Volume 4, Issue 1,   Pages 91-95 doi: 10.1007/s11705-009-0304-4

Abstract: The aim of this paper was to develop a cataplasma matrix that can be applicable to both watersolubleThe gellan gum and konjaku were employed as the scaffold materials of the matrix.With polyacrylic acid sodium and oligosaccharides as tacktifier, the formula of the cataplasma matrixFurthermore, the drug-compatibilities of the matrix were investigated with baicalin, berberine and curcuminThese results indicated that the obtained matrix had good drug-compatibility and drug-release properties

Keywords： drug-release     applicable     berberine     curcumin     different    

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Long acting carmustine loaded natural extracellular matrix hydrogel for inhibition of glioblastoma recurrence

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 4,   Pages 536-545 doi: 10.1007/s11705-021-2067-5

Abstract: glycolic acid groups is 75/25) nanoparticles were simultaneously loaded into natural extracellular matrix

Keywords： BCNU     glioblastoma recurrence     tumor resection     nanoparticles     hydrogel    

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numerical framework for underground structures in layered ground under inclined P-SV waves using stiffness matrix

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 1,   Pages 10-24 doi: 10.1007/s11709-022-0904-3

Abstract: The free-field responses are first obtained using the stiffness matrix method based on plane-wave assumptions

Keywords： underground structures     seismic response     stiffness matrix method     domain reduction method     P-SV waves    

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G-CNTs/PVDF mixed matrix membranes with improved antifouling properties and filtration performance

Xiaoyan Guo, Chunyu Li, Chenghao Li, Tingting Wei, Lin Tong, Huaiqi Shao, Qixing Zhou, Lan Wang, Yuan Liao

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 6, doi: 10.1007/s11783-019-1165-9

Abstract:

A novel nanocomposite OMWCNT-A-GO was synthesized by conjugating OMWCNT and GO.

The P-OMWCNT-A-GO membrane was fabricated by non-solvent induced phase inversion.

The P-OMWCNT-A-GO exhibits the best water flux, BSA rejection and flux recovery.

It should be due to the enhanced membrane pore size, porosity and hydrophilicity.

Keywords： carbon nanotubes     graphene oxide     mixed matrix membrane     nanohybrid     antifouling membrane     membrane hydrophilicity    

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Identification of dynamic stiffness matrix of bearing joint region

Feng HU, Bo WU, Youmin HU, Tielin SHI

Frontiers of Mechanical Engineering 2009, Volume 4, Issue 3,   Pages 289-299 doi: 10.1007/s11465-009-0064-3

Abstract: The paper proposes an identification method of the dynamic stiffness matrix of a bearing joint regionThe author deduces an identification model of the dynamic stiffness matrix from the synthetic substructureThe dynamic stiffness matrix of the bearing joint region can be identified by measuring the matrix ofagrees with experimental results, and there is very high reliability in the identified dynamic stiffness matrix

Keywords： frequency response function (FRFs)     dynamic stiffness     finite element     synthetic substructure method     joint region    

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Constant temperature control of tundish induction heating power supply for metallurgical manufacturing

Yufei YUE, Qianming XU, Peng GUO, An LUO

Frontiers in Energy 2019, Volume 13, Issue 1,   Pages 16-26 doi: 10.1007/s11708-018-0572-0

Abstract: Besides, an input harmonic current blocking strategy and a load voltage feedforward control are also

Keywords： tundish induction heating power supply (TIHPS)     constant temperature control     input harmonic current blocking    

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Title Author Date Type Operation

Robust generalized sidelobe canceller based on eigenanalysis and a MaxSINR beamformer

Quan-dong WANG, Liang-hao GUO, Wei-yu ZHANG, Sui-ling REN, Chao YAN

Journal Article

BGB-A445, a novel non-ligand-blocking agonistic anti-OX40 antibody, exhibits superior immune activation

Journal Article

Decellularized extracellular matrix mediates tissue construction and regeneration

Journal Article

Perspective of mixed matrix membranes for carbon capture

Shinji Kanehashi, Colin A. Scholes

Journal Article

Strengthening of reinforced concrete beams using fiber-reinforced cementitious matrix systems fabricated

Journal Article

A dynamic model of mobile concrete pump boom based on discrete time transfer matrix method

Wu REN, Yunxin WU, Zhaowei ZHANG

Journal Article

Glycosylation of dentin matrix protein 1 is critical for fracture healing via promoting chondrogenesis

Hui Xue, Dike Tao, Yuteng Weng, Qiqi Fan, Shuang Zhou, Ruilin Zhang, Han Zhang, Rui Yue, Xiaogang Wang, Zuolin Wang, Yao Sun

Journal Article

Role of salivary matrix metalloproteinase-8 (MMP-8) in chronic periodontitis diagnosis

Namita Gupta,N.D. Gupta,Akash Gupta,Saif Khan,Neha Bansal

Journal Article

Studies of fiber-matrix debonding

Navneet DRONAMRAJU,Johannes SOLASS,Jörg HILDEBRAND

Journal Article

A novel cataplasma matrix of traditional Chinese medicine

Jing TIAN, Xiaolei ZHANG, Xueqin ZHOU,

Journal Article

Long acting carmustine loaded natural extracellular matrix hydrogel for inhibition of glioblastoma recurrence

Journal Article

numerical framework for underground structures in layered ground under inclined P-SV waves using stiffness matrix

Journal Article

G-CNTs/PVDF mixed matrix membranes with improved antifouling properties and filtration performance

Xiaoyan Guo, Chunyu Li, Chenghao Li, Tingting Wei, Lin Tong, Huaiqi Shao, Qixing Zhou, Lan Wang, Yuan Liao

Journal Article

Identification of dynamic stiffness matrix of bearing joint region

Feng HU, Bo WU, Youmin HU, Tielin SHI

Journal Article

Constant temperature control of tundish induction heating power supply for metallurgical manufacturing

Yufei YUE, Qianming XU, Peng GUO, An LUO

Journal Article